Enzymology of amino acid biosynthesis. 

This is a long-standing and fun project that explores how bacteria and plants make the essential amino acids, such as lysine.  We have focused on the enzymology of amino acid biosynthesis, since the enzymes that make essential amino acids are good targets for the development of inhibitors that block their function, i.e. new antibiotics.  We collaborate with a long list enzymology and chemistry labs from around the world.